ABSTRACT
This paper reports two cases of schwannomas arising from the oral cavity. One is an intraoral ancient schwannoma located at the left cheek, which evolved over a period of 13 years. The tumor was a well-demarcated buccal mass, which was located in the left lower first premolar area, with an obliterated the buccal vestibule, leaving the overlying mucosa intact. The second case was a central intraosseous schwannoma located from the left lower 1st molar periapical area to the left 3rd molar periapical area. Pathologically, the first mass was composed of the spindle shaped tumor cells with wavy nuclei beneath the fibroconnective tissue of the gingiva but second case mass was not. Occasional nuclear pleomorphism was observed but mitosis or necrosis was absent. There were Antoni A and B areas along with strong, diffuse staining with the S-100 protein. Ancient schwannomas were diagnosed. Schwannoma is a slow-growing benign tumor, and an ancient schwannoma that shows cellular atypism is a variant of a schwannoma caused by purely degenerative changes. To date, only limited cases of ancient schwannomas in the oral cavity have been reported.
Subject(s)
Bicuspid , Cheek , Gingiva , Mitosis , Molar , Mouth , Mucous Membrane , Necrosis , Neurilemmoma , S100 ProteinsABSTRACT
Subject(s)
Humans , Cicatrix , Endoscopes , Facial Nerve , Follow-Up Studies , Jaw Fixation Techniques , Mandible , Mouth , Surgery, OralABSTRACT
Subject(s)
Ameloblastoma , Curettage , Enamel Organ , Facial Asymmetry , Mandible , Molar , Molar, Third , Odontogenic Cysts , Phenobarbital , Recurrence , Tooth , Tooth, ImpactedABSTRACT
Carcinoma ex pleomorphic adenoma is transformed at the incidence of 1-20% in pleomorphic adenoma and frequently recurred. It accounts for 10% of all malignant salivary tumors and its average age of occurrence is 60s. It will present in a large, long-standing pleomorphic adenoma or in one that was previously treated but has recurred. According to cell composition in malignant cell carcinoma, and clear cell adenocarcinoma. Most (75%) occur in parotid gland, while about 20% occur in the minor gland of the oral mucosa. The metastasis rate to regional lymph node is about 25%, and to distant organs about 33% and the 5-year survival rates are 40%. Though the treatment of the carcinoma ex pleomorphic adenoma is not established, it is treated ideally with and extensive resection, neck dissection, postoperative radiotherapy, and chemotherapy. When occurred in parotid gland, facial paralysis is reported. With a review of literatures, we report a case of carcinoma ex pleomorphic adenoma which operated with total parotidectomy and supraomohyoid neck dissection.
Subject(s)
Adenocarcinoma, Clear Cell , Adenoma, Pleomorphic , Incidence , Lymph Nodes , Mouth Mucosa , Neck Dissection , Neoplasm Metastasis , Parotid Gland , Survival RateABSTRACT